The attack - which shattered windows of surrounding buildings and caused some low-rise structures to collapse - struck a busy part of the city, close to a popular stationery market, the city's police headquarters and the offices of the European Union delegation and the High Peace Council.
An AFP reporter said he saw "lots of dead and wounded" people in a nearby hospital.
The Afghan Public Health Ministry spokesperson Mohammad Ismayeel Kawosi reportedly confirmed the casualty figures and stated that the injured persons have been rushed to different hospitals.
The Taliban has claimed responsibility for the attack. The Council was set up in 2010 to negotiate with the insurgent group.
The bomber drove an ambulance packed with explosives in a crowded area near the city's old interior ministry building just before 1pm local time, officials said. The overwhelmed medical staff were seen struggling to treat bloodied men, women and children who were lying in corridors.
"It's a massacre", said Dejan Panic, a coordinator with the NGO Emergency, which operates at hospital in city that treated victims.
Outside the hospital, people were carrying the injured on their backs and paramedics loaded several people into ambulances at once. "We're still counting dead bodies of last week's InterCon attack when a dozen plus killed & scores wounded in today's vehicle bombing on a public road", tweeted Lotfullah Najafizada.
Technology and health care companies are leading stocks broadly higher in midday trading on Wall Street. Another set of data showed new orders for key USA -made capital goods unexpectedly fell in December.
Rescuers took almost two hours to put out the fire as the search and rescue operation continued late into the night. Delhi Chief Minister Arvind Kejriwal's tweet read, "V sad to hear abt large no of casualties".
Meanwhile, this new interview comes after Sheeran announced that he is engaged to Seaborn on Instagram over the weekend. Despite their different career paths, the pair came together in 2015 when they bumped into each other in a bar in NY .
The World Economic Forum ( WEF ) was established as a not-for-profit foundation in Geneva, Switzerland, in 1971. Deputy President, Cyril Ramaphosa, and Finance Minister, Malusi Gigaba, at the Pre-WEF Davos Breakfast.
In Washington , McKenzie said the USA and Turkey were continuing talks about a "secure zone" but there had been no final decision. On Wednesday evening, rockets fired from Syria killed two people and wounded 11 more in the Turkish border province of Kilis.
If your device is compatible with iOS 11 or is already running that version of the Apple OS, then updating shouldn't be an issue. We recently learned that Apple had crossed the FCC regulatory hurdle and may release its HomePod smart speaker pretty soon.
Fox added it still anticipates "approval of the transaction by June 30, 2018" after the final deadline for decision ends on May 1. These could involve Sky News being spun off from Sky to prevent more Murdoch fingerprints on the country's journalism industry.
Last June, Tesco cut 1,200 jobs at its head office and 1,100 jobs in Cardiff, with the closure of a customer service centre. The changes affected workers in the supermarket's human ressource teams in Manchester, Coventry, Edinburgh, and London.
Will Gronk Be Cleared to Play in the Super Bowl?
The drive stalled when Brady was sacked by Dante Fowler Jr., and New England settled for Stephen Gostkowski's 31-yard field goal. No further update has been given by the Patriots since Gronkowski was ruled out for the game in the third quarter on Sunday.
Supermoon, Blue Moon, Lunar Eclipse All Coming Jan. 31
NASA has a very scientific not-at-all scary explanation for the crimson or copper hue you might see that night. Resident should set their alarms to 5:52 a.m., MST, on January 31 if they want view a total lunar eclipse.
3 executives from USA Gymnastics board resign
In December, it was revealed that USA Gymnastics paid 2012 Olympian McKayla Maroney to stay silent about her abuse by Nassar. In a YouTube video, Johnson East says being able to talk about the issue and make the video took her a long time.
End to shutdown in sight as Senate breaks Dem filibuster
He tweeted a call for McConnell to invoke the so-called "nuclear option" and thereby remove leverage for Senate Democrats. That, at least, was the offer the Senate majority leader, Mitch McConnell , made in order to break the stalemate.
Real Madrid enter battle for Liverpool midfielder
Spanish giants Real Madrid have been linked with a move for the Egyptian as they look to reinvent their frontline. Egypt's head coach Hector Cuper would later claim in December that he was told of Madrid's interest in Salah .
Sydney train crash sends passengers flying, injures 16
Passenger Jaiden Ruttley, who was towards the back of the train , said it felt like "the whole train had lifted up in the air". He said the 10 other commuters had suffered less serious injuries but predicted the number of those injured would rise.
Underdog Eagles face a stiff challenge today against Minnesota
Jenkins is joined by Rodney McLeod in the back end of the defense to form one of the most efficient safety tandems in the NFL . One is to live with them and the other is to get rid of officials that turn out to be repeat offenders. "There are nerves.
Brave Halep wins marathon to reach fourth round
Halep wasted chances to serve for the match in the ninth, 11th and 15th games, then had to save three match points in the 22nd. Muguruza never looked comfortable in the match , double-faulting on break point in the second set and had 43 unforced errors.